Table 2. Relationships between FSTL1 expression in the tumor stroma and patient characteristics.
| Characteristics | Tumor tissue FSTL1 in full scan (n=310), n (%) | Tumor tissue FSTL1 in stroma (n=310), n (%) | |||||
|---|---|---|---|---|---|---|---|
| ≤6.5 (n=131) | >6.5 (n=179) | P | ≤3.17 (n=163) | >3.17 (n=147) | P | ||
| Age (years) | 0.253 | 0.057 | |||||
| ≤59 | 73 (55.7) | 88 (49.2) | 93 (57.1) | 68 (46.3) | |||
| >59 | 58 (44.3) | 91 (50.8) | 70 (42.9) | 79 (53.7) | |||
| Sex | 0.360 | 0.823 | |||||
| Female | 46 (35.1) | 72 (40.2) | 63 (38.7) | 55 (37.4) | |||
| Male | 85 (64.9) | 107 (59.8) | 100 (61.3) | 92 (62.6) | |||
| Primary tumor site | 0.004 | <0.001 | |||||
| Colon | 74 (56.5) | 129 (72.1) | 122 (74.8) | 81 (55.1) | |||
| Rectum | 57 (43.5) | 50 (27.9) | 41 (25.2) | 66 (44.9) | |||
| Primary tumor size (cm) | 0.087 | 0.975 | |||||
| ≤4.5 | 64 (48.9) | 105 (58.7) | 89 (54.6) | 80 (54.4) | |||
| >4.5 | 67 (51.1) | 74 (41.3) | 74 (45.4) | 67 (45.6) | |||
| TNM stage | <0.001 | 0.215 | |||||
| II | 59 (45.0) | 42 (23.5) | 48 (29.4) | 53 (36.1) | |||
| III/IV | 72 (55.0) | 137 (76.5) | 115 (70.6) | 94 (63.9) | |||
| Histological grade | 0.128 | 0.251 | |||||
| Well/moderate | 105 (80.2) | 155 (86.6) | 133 (81.6) | 127 (86.4) | |||
| Poor | 26 (19.8) | 24 (13.4) | 30 (18.4) | 20 (13.6) | |||
| CEA level (ng/mL) | 0.608 | 0.647 | |||||
| ≤5 | 56 (44.1) | 72 (41.1) | 65 (41.1) | 63 (43.8) | |||
| >5 | 71 (55.9) | 103 (58.9) | 93 (58.9) | 81 (56.2) | |||
| CA19-9 level (U/mL) | 0.007 | 0.116 | |||||
| ≤35 | 99 (79.2) | 112 (64.7) | 105 (66.9) | 106 (75.2) | |||
| >35 | 26 (20.8) | 61 (35.3) | 52 (33.1) | 35 (24.8) | |||
FSTL1, follistatin-like protein 1; CEA, carcinoembryonic antigen before primary tumor resection; CA19-9, cancer antigen 19-9 before primary tumor resection.