Figure 1.

The relationship between UBE2L3 and systemic lupus erythematosus (SLE). (a) Regional association plots of the UBE2L3 locus. The regional plots were plotted based on the published data of the SLE genome‐wide association studies (GWAS)4 using the locuszoom website tool (http://locuszoom.sph.umich.edu//). (b) UBE2L3 was differentially expressed between SLE cases and controls according to gene expression profile data from the GEO database. (c,d) UBE2L3 gene expression was causally associated with SLE according to the SMR analysis.