. 2019 Apr 25;9(6):5268–5278. doi: 10.1021/acscatal.9b00918

Table 3. Screening of H₈-BINAP Derivatives in the Asymmetric C–H Arylation of Complex 1a with 2a.

Entry	Ligand	Yield 3aa (%)^a	er3aa^b	Yield 4aa (%)^a
1	(S)-L10	42	7:93	27
2	(S)-L11	33	46:54	16
3	(S)-L12	27	46:54	7
4	(S)-L13	37	27:73	22
5	(S)-L14	33	50:50	19
6	(S)-L15	46	10:90	24
7	(S)-L16	37	20:80	20
8	(S)-L17	37	27:73	22
9	(S)-L18	40	18:82	22

Determined by ¹H NMR spectroscopy using 1,3,5-trimethoxybenzene as internal standard.

Determined by HPLC (Chiralpak IB hexane/isopropyl alcohol).

Table 3. Screening of H8-BINAP Derivatives in the Asymmetric C–H Arylation of Complex 1a with 2a.