Figure 2. Peak areas of tract disruption within the ascending arousal network.

Blue shows 3D reconstruction of median normalized tracts in controls connecting the brainstem tegmentum seed to a combined target including the hypothalamus (Hy), thalamus (Th), and basal forebrain (BF) (binarized surface, median normalized tract count > 0.0005). Red shows voxels with significantly fewer normalized tracts in patients relative to controls (Benjamini-Hochberg false discovery rate–adjusted p_c < 0.05). DoC = disorders of consciousness; P = pons.