Table 1.
Mean apoptosis index obtained for CHO-K1 and HeLa cells after 24 h of treatment with indirubin.
| Apoptosis Index (%) Mean ± SD |
||
|---|---|---|
| Treatments | CHO-K1 | HeLa |
| PBS | 9.70 ± 0.02 | 6.17 ± 1.15 |
| DXR 0.3 μM | 32.30 ± 0.07* | 12.17 ± 1.44* |
| IRN 0.1 μM | 14.75 ± 0.03 | 7.50 ± 1.41 |
| IRN 0.5 μM | 11.17 ± 0.01 | 7.50 ± 1.41 |
| IRN 1.0 μM | 9.90 ± 0.02 | 7.33 ± 0.29 |
| IRN 5.0 μM | 9.80 ± 0.03 | 5.67 ± 1.04 |
| IRN 10.0 μM | 12.00 ± 0.04 | 8.17 ± 1.04 |
SD: standard deviation; PBS: phosphate-buffered saline, negative control; DXR: doxorubicin, positive control; IRN: indirubin.
*
Indicates significant difference compared to the negative control group (p < 0.05, ANOVA followed by Tukey’s test).