Figure 1.

Kaplan-Meier curves comparing risk of coronary heart disease for different phenotypes of obstructive airway disease in the Copenhagen General Population Study. (A) Asthma with early onset or late-onset versus no respiratory disease. (B) COPD with FEV₁<50%, COPD with FEV₁≥50%, versus no respiratory disease. (C) ACO with late-onset asthma and FEV₁≥50%, ACO with early onset asthma and FEV₁≥50%, COPD with FEV₁≥50%, vs no respiratory disease. (D) ACO with late-onset asthma and FEV₁<50%, ACO with early onset asthma and FEV₁<50%, COPD with FEV₁<50%, versus no respiratory disease. ACO, asthma-COPD overlap; CHD, coronary heart disease; COPD, chronic obstructive pulmonary disease; FEV₁, forced expiratory volume in one second; GOLD, Global Initiative for Chronic Obstructive Lung Disease.