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. 2016 Sep 27;55(1):146–155. doi: 10.1080/13880209.2016.1231695

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© 2016 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/Licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 5. — Histological examination of the thoracic aorta, H&E 400×. (A) DMSO-treated rat thoracic aorta showing normal architecture with regular vascular morphology. (B) L-Methionine-treated group showing EDN IT and PSMC. Proliferation of connective tissue, disruption of normal fibrillar pattern and increase of matrix (M) tissue is also seen in adventitia layer of the aorta. (C) HSP-25 mg/kg group showing MEDN and PSMC similar to L-methionine group. (D–G) HSP-50,100 mg/kg, HSP-Per se and donepezil-treated groups showing NAI with regular morphology of the aorta same as the control group.