Table 3.

IC₅₀ for reductions in the total cell number and cell cycle effects of compounds 7b, 10e, and Sunitinib.

	IC50 (µM) for reductions in the total cell number		IC50 (µM) for reduction in Rb phosphorylation
Compound No.	24 h	48 h	24 h	48 h	Cell cycle effects
7b	12.67 ± 13.6	8.08 ± 0.95	12.07 ± 0.6	13.56 ± 0.6	G1 decreased and G2/M-phases increased
10e	7.38 ± 1.04	7.27 ± 1.15	7.59 ± 0.38	12.46 ± 2.1	G1 increased and G2/M-phases decreased
Sunitinib	12.54 ± 9.82	3.48 ± 0.61	3.18 ± 0.07	14.01 ± 0.6	G1 decreased and G2/M-phases increased