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Cancer cell growth inhibitory activity of compounds 7b, 10e, and Sunitinib towards sensitive (A-549) and resistant (NCI-H69AR) cell lines.
| IC50 (µM) |
|||
|---|---|---|---|
| Compound No. | Sensitive A-549 | Resistant NCI-H69AR | Fold resistant |
| 7b | 3.8 ± 0.67 | 16.0 | 4.2 |
| 10e | 4.1 ± 0.61 | 16.6 | 4.0 |
| Sunitinib | 3.1 ± 0.9 | 5.8 ± 0.52 | 1.9 |
