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. 2016 Oct 8;55(1):173–183. doi: 10.1080/13880209.2016.1233568

Table 3.

Frequency profile of CA induced by endosulfan alone and in combination with column eluted fractions of active P. hexandrum extracts for different time intervals to evaluate the antimutagenicity in C. carassius.

      Classical aberrations
Non-classical aberrations
 
Exp. Treatment TMS Csb Ctb Frg Scu Dic Mla Stp Cmt Total aberrations mean (%)± S.D.
48 Cont. 1 105 1 1 1 2.85 ± 0.212
  Cont. 2 102 1 1 1 2.94 ± 0.162
  Endosulfan 117 2 2 1 1 1 2 7.69 ± 0.37Bb
  EE-F1 103 1 1 1 1 2 5.82 ± 0.27Bb2
  EE-F2 106 1 1 1 1 1 1 5.66 ± 0.23Bb2
  EE-F3 113 1 1 2 1 1 5.30 ± 0.26Bb2
  EE-F4 101 1 1 1 1 1 4.95 ± 0.21Bb2
  EE-F5 107 1 2 1 1 1 5.60 ± 0.26Bb2
  ME-F1 116 1 1 1 1 1 1 5.17 ± 0.22Bb2
  ME-F2 118 1 1 2 1 4.23 ± 0.242
  ME-F3 113 2 1 1 1 4.42 ± 0.24A2
  ME-F4 114 1 1 1 1 1 1 5.26 ± 0.22Bb2
  ME-F5 115 1 2 2 1 1 6.08 ± 0.30Bb1
72 Cont. 1 104 1 1 1 2.88 ± 0.162
  Cont. 2 101 1 1 1 2.97 ± 0.172
  Endosulfan 110 2 2 1 1 1 2 1 9.09 ± 0.37Bb
  EE-F1 120 1 1 1 2 2 1 6.66 ± 0.31Bb2
  EE-F2 100 1 1 1 1 1 1 6.00 ± 0.23Bb2
  EE-F3 119 2 1 2 1 1 5.88 ± 0.29Bb2
  EE-F4 102 1 1 1 1 1 4.90 ± 0.21Bb2
  EE-F5 108 1 2 2 1 1 6.48 ± 0.31Bb2
  ME-F1 120 1 1 2 2 1 5.83 ± 0.29Bb2
  ME-F2 114 1 1 1 1 1 4.38 ± 0.202
  ME-F3 107 2 1 1 1 1 5.60 ± 0.26Bb2
  ME-F4 109 1 1 1 1 1 1 5.50 ± 0.22Bb2
  ME-F5 103 1 2 1 1 1 1 6.79 ± 0.28Bb2
96 Cont. 1 119 2 1 1 3.36 ± 0.222
  Cont. 2 108 2 1 1 3.70 ± 0.232
  Endosulfan 107 3 2 1 1 2 2 1 1 12.14 ± 0.47Bb
  EE-F1 109 1 1 2 1 1 1 1 1 8.25 ± 0.33Bb2
  EE-F2 111 2 1 1 1 1 1 1 7.20 ± 0.29Bb2
  EE-F3 112 1 1 1 2 2 1 7.14 ± 0.32Bb2
  EE-F4 105 1 1 2 1 1 5.71 ± 0.27Bb2
  EE-F5 106 1 2 1 1 1 1 1 7.54 ± 0.29Bb2
  ME-F1 113 2 3 2 1 7.07 ± 0.39Bb2
  ME-F2 103 1 2 1 1 4.85 ± 0.252
  ME-F3 104 2 1 1 1 1 1 6.73 ± 0.28Bb2
  ME-F4 108 2 2 1 2 1 7.40 ± 0.35Bb2
  ME-F5 116 1 2 1 2 2 1 7.75 ± 0.35Bb2

Exp: exposure time in hours; TMS: total metaphasic plates studied; Csb: chromosome break; Ctb: chromatid break; Frg: fragment; Scu: sister chromatid union; Dic: dicentric; Mla: multiple aberrations; Stp: stickiness and pulverization; Cmt: c metaphase; Cont. 1: negative control (tap water); Cont. 2: solvent control; EE-F1,2,3,4, and 5 designate the ethyl acetate extract fractions 1,2,3,4, and 5 (15 mg/L each), respectively, ME-F1,2,3,4, and 5 represent the methanol extract fractions 1,2,3,4, and 5 (10 mg/L), respectively.