Table 6.

Minimal inhibitory concentration (MIC) of selected HTS hits against different microorganisms.

HTS hit	C. ammoniagenes (μM)	M. tuberculosis (μM)	S. pneumoniae (μM)
1	>64	>64	>64
2	>64	>64	>64
9	2	16	1-2
11	>64	>64	>64
14	0.25	8	2
15	32	>64	64
17	8	>64	>64
24	16–32	16–32	>64
27	64	>64	>64
29	0.125	16–32	1
31	32–64	>64	>64
32	8	>64	64
33	0.125	2–4	0.5
35	16–32	>64	64
37	>64	>64	>64
38	32	>64	16–32
47	2–4	8	4

The FMNAT hits are shown in italics. Compounds were assayed in the 0.125–64 μM range.