Fig. 6. (a) Schematic illustration of the in vivo corneal healing process using NO-releasing BP1 vesicle-based eye drops. (b) Representative photographs of the wounded corneas treated with PBS buffer, untreated BP1 vesicles, irradiated BP1 vesicles, and GSNO, respectively. After each treatment, the corneas were stained with 0.5% sodium fluorescein solution and were imaged by using a Dino-lite hand-held microscope. (c) Quantitative analysis of the wounded areas in (b) using ImageJ software. Values are presented as mean ± s.d. (n = 4). p values were calculated in comparison with the group treated with PBS, **p < 0.01; ***p < 0.001.
