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Triptolide inhibits Th2-predominant cytokines in the tumor microenvironment. RT-PCR (a) and ELISA (b) analyses were performed to determine the Th2 cytokine milieu in M2-poralized THP-1 macrophages. RT-PCR (c) and ELISA (d) analyses were performed to determine the level of IL-10 in the AOM/DSS mouse serum and colon tissue. Colon tissue with a normal histology was used as a control . *P < .05, **P < .01, and ***P < .001 compared to model group.
