Table 2.

The targetable genotype in different study populations.

Targetable genomic alterations	The cBioportal data base (n = 773)					Chinese lung adenocarcinoma (n = 177)
Age groups	≤45, y, No.(%)		>45, y, No.(%)		P	≤45, y, No.(%)		>45, y, No.(%)		P
Total	42		731		/	87		90		/
EGFR	13	30.95	127	17.37%	.037	49	56.32	40	44.44	.134
ALK	4	9.52	21	2.87%	.041	14	16.09	1	1.11	.001
ROS1	2	4.76	14	1.92%	.214	0	0.00	3	3.33	.246
RET	4	9.52	8	1.09%	.003	1	1.15	1	1.11	1.000
BRAF-V600E	1	2.38	15	2.05%	.595	1	1.15	0	0.00	.492
MET	1	2.38	40	5.47%	.719	0	0.00	2	2.22	.497
ERBB2	0	0.00	22	3.01%	.626	5	5.75	2	2.22	.272
KRAS	2	4.76	236	32.28%	<.001	3	3.45	17	18.89	.002
Wide type	15	35.71	248	33.93%	.867	14	16.09	24	26.67	.101

Note: P < .05 was used to define statistical significance.