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Genomic evaluations of C-KIT and PDGFRA mutation by sequencing.
(a) Sequence analysis showed that a missense mutation in the exon 13 of C-KIT (NM 000222.2: c.1886C>G (p.A629G)) from previously postoperative specimens (No.09085396) (black arrow). (b) A missense mutation (NM 006206.4: c.2525A>T (p.D842V)) in exons 18 of PDGFRA was identified in the last surgical tissues of our hospital (No.1304736) (black arrow).
