Figure 1.
Clinical efficacy of HDC/IL-2 in patients with aberrant or normal karyotype AML. Analysis of the impact of HDC/IL-2 treatment on leukemia-free survival (LFS) and overall survival (OS) in a phase III trial. The Kaplan-Meier plots show LFS (a) or OS (b) in patients in CR1 with known karyotype (n = 225). Figures (c) and (d) show corresponding results in patients with normal karyotype AML who were below or above 60 years old at random assignment. The logrank test was employed for statistical analysis.