Table 1.
Treatment groups.
| Group | Vaccine* | Dose Month 0 |
Dose Month 1 |
Dose Month 2 |
Antimalarial‡ | Group name† |
Participants |
|---|---|---|---|---|---|---|---|
| 1 | RTS,S/AS01B | Single standard dose (0.5mL) | Single standard dose (0.5mL) | Fractional dose (0.1mL) | B-SSF | 21 | |
| 2 | RTS,S/AS01E | Double standard dose (1.0mL) | Double standard dose (1.0mL) | Double Fx dose (0.2mL) | EE-SSF | 21 | |
| 3 | RTS,S/AS01E | Single standard dose (0.5mL) | Single standard dose (0.5mL) | Single standard dose (0.5mL) | E-SSS | 30 | |
| 4 | RTS,S/AS01E | Single standard dose (0.5mL) | Single standard dose (0.5mL) | Single standard dose (0.5mL) | DHA-PIP+PQ | E-SSS+D | 30 |
| 5 | RTS,S/AS01E | Single standard dose (0.5mL) | Single standard dose (0.5mL) | Fractional dose (0.1mL) | E-SSF | 30 | |
| 6 | RTS,S/AS01E | Single standard dose (0.5mL) | Single standard dose (0.5mL) | Fractional dose (0.1mL) | DHA-PIP+PQ | E-SSF+D | 30 |
| 7 | RTS,S/AS01E | Single standard dose (0.5mL) | Fractional dose (0.1mL) | DHA-PIP+PQ | E-SF+D | 31 |
* RTS,S/AS01B = adult dose, RTS,S/AS01E = paediatric dose‡DHA-PIP: Dihydroartemisinin-piperaquine; PQ: primaquine † B: RTS,S/AS01B; E: RTS,S/AS01E; EE: double dose of RTS,S/AS01E; S: standard dose; F: fractional dose; +D: DHA-PIP+PQ