Table 2.
Composition of Vaxchora™ vaccine.
| Components | Properties | Dosage |
|---|---|---|
| Packet 1 | ||
| Viable CVD 103-HgR | Active ingredient | 4 × 108 to 2 × 109 cfu |
| Sucrose | Cryoprotectant | ≤165.37 mg |
| Sodium chloride | Stabilizer | ≤17.11 mg |
| Hy-Case SF | Stabilizer (cryoprotectant) | ≤17.11 mg |
| Ascorbic acid | Stabilizer (antioxidant) | ≤8.55 mg |
| Dried lactose | Stabilizer (desiccant) and bulking agent | ≤2.09 g |
| Packet 2 | ||
| Sodium bicarbonate | Buffer | 2.16–2.41 g |
| Sodium carbonate | Buffer | 0.24–0.49 g |
| Ascorbic acid | Buffer | 1.50–1.80 g |
| Dried lactose | Flow ability | 0.18–0.22 g |