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. Author manuscript; available in PMC: 2020 Apr 1.
Published in final edited form as: Nat Genet. 2019 Oct;51(10):1429–1433. doi: 10.1038/s41588-019-0500-1

Figure 3. GO-CAM model of initial steps in the canonical Wnt signaling pathway.

Figure 3.

This diagram is a screenshot of the interface of the web-based curation platform (Noctua) for GO-CAM models. In this view, each molecular activity is represented by a box, and some of the properties in Figure 2 (the active entity, the location and the target entity) are “folded” into that box. The beta-catenin destruction complex is not folded into its activity box, so that the constituent gene products (e.g. AXIN1) are visible. Noctua is available at http://noctua.geneontology.org (the URL for this model is http://model.geneontology.org/596ef51500000088).