Table 1.
Clinical and Genetic Characteristics for 958 Patient-Admissionsa
| Characteristic | Caucasian N = 802 |
African American N = 156 |
|---|---|---|
| Age, median [IQR], y | 62 [52–71] | 59 [48–68] |
| Female, N (%) | 371 (46%) | 75 (48%) |
| Hospital length of stay, median [IQR], days | 13 [7–26] | 8 [5–17] |
| Days assessed with CAM-ICU/RASSb | 9 [5–18] | 6 [3–12] |
| Deliriumc | ||
| Ever, N (%) | 675 (84%) | 120 (77%) |
| Duration, median [IQR], daysd | 6 [3–13] | 4 [2–9] |
| Comac | ||
| Ever, N (%) | 274 (34%) | 35 (22%) |
| Duration, median [IQR], dayse | 1 [1–3] | 1 [1–2] |
| Caucasian mitochondrial DNA haplogroups | ||
| H | 392 (49%) | - |
| IWX | 54 (7%) | - |
| J | 66 (8%) | - |
| T | 101 (13%) | - |
| Uk | 164 (20%) | - |
| Other | 25 (3%) | - |
| African mitochondrial DNA haplogroups | ||
| L1 | - | 24 (15%) |
| L2 | - | 38 (24%) |
| L3 | - | 49 (31%) |
| Other | - | 45 (29%) |
CAM-ICU Confusion Assessment Method for the ICU, ICU intensive care unit, IQR interquartile range, RASS Richmond Agitation-Sedation Scale.
a
Eight hundred ten patients accounted for 958 hospital admissions.
b
Per usual care, all ICU patients were assessed with the CAM-ICU and RASS at least once per nursing shift (i.e., once every 8 hours) until discharge from the ICU.
c
During the 14-day study period beginning on the day of first CAM-ICU and/or RASS assessment.
d
Among patient-admissions when delirium occurred during the study period.
e
Among patient-admissions when coma occurred during the study period.