Table 4.

Periprocedural Adverse Events among Asymptomatic Patients Undergoing Carotid Stenting in C2R for Primary Atherosclerosis, Stratified by Potential CREST-2 Trial Eligibility

Adverse event rates - n (%)	All asymptomatic patients 1180* (100%)	CREST-2 trial ineligible 916 (77.6%)	CREST-2 trial eligible 264 (22.4%)
Stroke or death	16 (1.4)	14 (1.5)	2 (0.8)
Any stroke, regardless of laterality	12 (1.0)	11 (12)	1 (0.4)
Stroke ipsilateral to the index artery	9 (0.8)	8 (0.9)	1 (0.4)
Stroke contralateral to the index artery	5 (0.4)	5 (0.6)	0 (0)
Death	4 (0.3)	3 (0.3)	1 (0.4)
Stroke, death, or myocardial infarction	18 (1.5)	16 (1.8)	2 (0.8)
Myocardial infarction (MI)	2 (0.2)	2 (0.2)	0 (0)
Stroke, death, MI, or major† access site complications	27 (2.3)	23 (2.5)	4 (1.5)
Major access site complications	9 (0.8)	7 (0.8)	2 (0.8)

^*1180 asymptomatic patients out of the total 2141 C2R patients with primary atherosclerosis

^†Access site complications are considered major if there is a need for blood transfusion or surgical evacuation/repair