Fig 8. Protection of hamsters against wt RSV challenge.
Hamsters immunized with the indicated viruses in the experiment described for Fig 7 were challenged IN with 106 PFU of wt RSV at day 30 post-immunization. The animals were sacrificed on day 3 post-challenge, and the titers of challenge virus in the nasal turbinates (A) and lungs (B) were determined by immunoplaque assay. The RSV titer is shown for each hamster (filled circles) with the group mean titer indicated by a horizontal line. Dashed line indicates the assay detection limit.