Table 1. Patient characteristics.
| Characteristic | Total, No. (%) | Age, No. (%) | P Value | Chi-square Statistic | |
|---|---|---|---|---|---|
| <70 | > = 70 | ||||
| Patients | 415 (100) | 289 (100) | 126 (100) | NA | NA |
| Sex | 0.341 | 0.906 | |||
| Female | 245 (59) | 175 (61) | 70 (56) | ||
| Male | 170 (41) | 114 (39) | 56 (44) | ||
| Race | 0.127 | 9.956 | |||
| African American | 10 (2) | 6 (2) | 4 (3) | ||
| American Indian or Alaska Native | 2 (0) | 1 (0) | 1 (1) | ||
| Asian | 136 (33) | 107 (37) | 29 (23) | ||
| White | 247 (60) | 161 (56) | 86 (68) | ||
| Native Hawaiian or Other Pacific Islander | 3 (1) | 3 (1) | 0 (0) | ||
| Other | 12 (3) | 8 (3) | 4 (3) | ||
| Unknown/Declined to Answer | 5 (1) | 3 (1) | 2 (2) | ||
| Ethnicity | 0.150 | 3.796 | |||
| Hispanic or Latino | 40 (10) | 28 (10) | 12 (10) | ||
| Not Hispanic or Latino | 369 (89) | 259 (90) | 110 (87) | ||
| Unknown/Declined to Answer | 6 (1) | 2 (1) | 4 (3) | ||
| Smoking Status | 0.036 | 8.550 | |||
| Never | 212 (51) | 159 (55) | 53 (42) | ||
| Light (<10 pack years) | 42 (10) | 31 (11) | 11 (9) | ||
| Medium (10–29 pack years) | 74 (18) | 44 (15) | 30 (24) | ||
| Heavy (> = 30 pack years) | 87 (21) | 55 (19) | 32 (25) | ||
| Stage | 0.004 | 13.595 | |||
| I | 15 (4) | 7 (2) | 8 (6) | ||
| II | 14 (3) | 5 (2) | 9 (7) | ||
| III | 17 (4) | 10 (3) | 7 (6) | ||
| IV | 369 (89) | 267 (92) | 102 (81) | ||
| EGFR (L858R/exon 19 deletion) * | 0.059 | 3.559 | |||
| Alteration | 177 (43) | 132 (46) | 45 (36) | ||
| Tested Negative | 238 (57) | 157 (54) | 81 (64) | ||
| ALK (Rearrangement)* | 0.001 | 10.349 | |||
| Positive | 28 (7) | 27 (10) | 1 (1) | ||
| Tested Negative | 349 (93) | 235 (90) | 114 (99) | ||
| ROS1 (Rearrangement)* | 0.233 | 1.422 | |||
| Positive | 3 (1) | 3 (2) | 0 (0) | ||
| Tested Negative | 254 (99) | 172 (98) | 82 (100) | ||
| BRAF (V600E)* | 0.319 | 0.995 | |||
| Positive | 7 (2) | 6 (3) | 1 (1) | ||
| Tested Negative | 281 (98) | 194 (97) | 90 (99) | ||
| MET (exon 14 splice-site/deletion)* | 0.022 | 5.228 | |||
| Positive | 7 (2) | 2 (1) | 5 (5) | ||
| Tested Negative | 280 (98) | 194 (99) | 86 (95) | ||
| KRAS | <0.001 | 12.410 | |||
| Positive | 97 (28) | 53 (22) | 44 (40) | ||
| Tested Negative | 255 (72) | 189 (78) | 66 (60) | ||
| TP53 | 0.306 | 1.046 | |||
| Positive | 140 (49) | 99 (52) | 41 (45) | ||
| Tested Negative | 143 (51) | 93 (48) | 50 (55) | ||
*Only patients who had genomic test results were counted for each gene. Total number of patients with ALK, ROS1, BRAF, MET, KRAS and TP53 tested were 377, 257, 288, 287, 352, and 283 respectively.