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. 2019 May 17;105(2):457–467. doi: 10.3324/haematol.2018.212266

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Figure 1. — Decreased sialylation of B cells and kidney toxicity following systemic 3F_ax-Neu5Ac treatment. Peripheral blood B cells were stained with SNA (A and B) or PNA (C and D) on the seventh day of dosing (A and C) and after seven days of recovery post last injection (B and D). Bars represent mean±Standard Error of Mean of three independent experiments. The one-way ANOVA was used to determine statistical significance with Dunnett’s multiple comparison post-hoc testing. **P<0.01; ****P<0.0001; ns: non-significant. MFI: median fluorescence intensity. (E) Representative images of Hematoxylin & Eosin stained kidneys taken after seven days of recovery. Images were taken at 20x magnification of four representative mice.