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. 2020 Jan 9;65(3):109–121. doi: 10.5387/fms.2019-12

Fig. 2.

Fig. 2.

The expression of RAGE in the aortic atherosclerotic plaques of WHHLMI rabbits with aging by immunohistochemistry (A) and Western blotting (B). A: RAGE expression at 1, 3, 7 and 14 months. B: Western blotting of RAGE in the aortae of 3-month-WHHLMI rabbits. Immunoblot was probed with a specific goat anti-RAGE antibody (lane 2), whereas nonimmunized normal goat IgG was used as a negative control antibody (lane 1). RAGE was identified at the band of 46 kD in the atherosclerotic lesions of 3-month-WHHLMI rabbit. C and D: Quantitative analysis of RAGE expression of area (C) and proportion (D) in the atherosclerotic plaques of WHHLMI rabbits at 1, 3, 7 and 14 months (n=4 to 6, each month). Measured values are represented as mean±S.D. *P<0.05.