Table 1:
Baseline demographic and clinical data from lead-in period
| Thymectomy (n=30) | Non-thymectomy (n=51) | p-value | ||
|---|---|---|---|---|
| Age at diagnosis (years) | 49.4 (15.2) | 65.8 (11.9) | <0.001 | |
| Sex (female) | 15 (50%) | 20 (40%) | 0.38 | |
| Race/ethnicity | Caucasian | 23 (96%) | 36 (86%) | 0.59 |
| African-American | 1 (4%) | 4 (10%) | ||
| Asian-American | 0 (0%) | 1 (2%) | ||
| Other/unknown | 0 (0%) | 1 (2%) | ||
| Treating neuro-ophthalmologist | 1 | 25 (83%) | 26 (52%) | |
| 2 | 4 (13%) | 23 (46%) | ||
| 3 | 1 (1%) | 1 (2%) | ||
| Acetylcholine receptor binding antibody positive (>0.4 nmol/L) | 18 (58%) | 35 (70%) | 0.27 | |
| Symptom duration at diagnosis (months) | 7.2 (17.5) | 4.7 (7.5) | 0.38 | |
| Symptom severity (time-weighted) | 1.19 (0.89) | 1.08 (0.77) | 0.55 | |
| Prednisone dose (time-weighted) | 3.11 (5.56) | 1.12 (3.52) | 0.053 | |
| Steroid-sparing agent | 4 (13%) | 3 (6%) | 0.26 | |
Summary statistics are shown as mean and standard deviation for continuous variables and number and frequency for categorical variables. P-values are for t-test for continuous variables and chi-squared test for categorical variables.