Table 3.
Pre-Angiography Plasma and Urine Biomarker Levels by CA-AKI Status
| Plasma Biomarker | Urine Biomarker | |||||||
|---|---|---|---|---|---|---|---|---|
| Median [IQR], pg/mL | P | Median [IQR], pg/mL | P | |||||
| CA-AKI | No CA-AKI | Unadj | Adj* | CA-AKI | No CA-AKI | Unadj | Adj* | |
| KIM-1 | 430 (295, 713) | 319 (190, 593) | 0.002 | 0.004 | 1460 (767, 2633) | 1419 (731, 2805) | 0.9 | 0.9 |
| NGAL | 232 (168, 297) | 230 (175, 299) | 0.9 | 0.6 | 20 (9, 41) | 24 (12, 51) | 0.4 | 0.3 |
| IL-18 | 347 (265, 447) | 316 (245, 408) | 0.09 | 0.1 | 22 (10, 38) | 21 (12, 38) | 0.8 | 0.9 |
| MCP-1 | 218 (168, 265) | 218 (181, 271) | 0.5 | 0.3 | 183 (115, 302) | 210 (119, 374) | 0.3 | 0.4 |
| UMOD | 68 (49, 87) | 71 (50, 97) | 0.3 | 0.3 | 2776 (1683, 4606) | 2453 (1548, 3862) | 0.2 | 0.3 |
| YKL-40 | 108251 (54743, 205041) | 94598 (54166, 178090) | 0.4 | 0.5 | 400 (137, 1202) | 406 (137, 1255) | 0.9 | 0.7 |
Urine creatinine-corrected results in Table S1
*
Adjusted for Urinary Albumin-Creatinine Ratio and baseline eGFR
Adj, adjusted; unadj, unadjusted; KIM-1 [kidney injury marker 1], NGAL [neutrophil gelatinase-associated lipocalin], IL-18 [interleukin 18], MCP-1 [monocyte chemoattractant protein 1], UMOD [uromodulin], and YKL-40 [chitinase-3-like protein 1].