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. Author manuscript; available in PMC: 2021 Feb 1.

Published in final edited form as: J Inorg Biochem. 2019 Nov 13;203:110922. doi: 10.1016/j.jinorgbio.2019.110922

Table 2.

Cell Viability Data for Treatment with 1_A–3_A in the Dark and upon Irradiation for One Hour with Blue Light (450 nm)^a

	vs MDA-MD-231 (breast CSC)			vs MCF7 (breast cancer)
compound	IC₅₀ dark	IC₅₀ light	PI^b	IC₅₀ dark	IC₅₀ light	PI
1_A	1010	290	3.5	>500	>500	~1
2_A	280	83	3.3	490	180	2.8
3_A	190	3.7	52	490	4.1	120

	MCF10A (normal)			vs HeLa (cervical cancer)
compound	IC₅₀ dark	IC₅₀ light	PI^b	IC₅₀ dark	IC₅₀ light	PI
1_A	>500	210	>2.4	148	202	0.73
2_A	110	13	9	1440	383	3.8
3_A	58	29	2	730	120	6

^a

IC₅₀ values are in μM and were previously reported.[14]

^b

The phototoxicity index (PI) is the ratio of IC₅₀ in the dark to IC₅₀ in the light.