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. Author manuscript; available in PMC: 2021 Mar 1.
Published in final edited form as: J Appl Toxicol. 2019 Oct 21;40(3):342–351. doi: 10.1002/jat.3907

Table 6.

Crude and adjusted linear regression between breast cancer and lifestyle factors, arsenic urinary levels, and YAP polymorphisms.

β 95% CI P-value
Crude Adjusted Crude Adjusted Crude Adjusted
Lifestyle factors
 Smoking 0.176 0.147 0.02 0.32 0.00 0.29 0.024 0.047
 Type of drinking water 0.199 0.151 0.07 0.32 0.02 0.27 0.002 0.020
Urinary arsenic metabolites
 AsIII 0.034 0.02 0.00 0.06 0.00 0.05 0.017 0.049
 AsV 0.032 0.02 0.01 0.05 0.00 0.04 0.003 0.008
 iAs 0.023 0.01 0.00 0.03 0.00 0.03 0.001 0.006
 MMAV 0.005 0.002 −0.00 0.01 −0.00 0.01 0.362 0.623
 DMAV 0.002 0.001 0.00 0.00 −0.00 0.00 0.047 0.17
 Total As 0.001 0.001 0.00 0.00 −0.00 0.00 0.038 0.142
As methylation profile
 First methylation −0.077 −0.07 −0.12 −0.03 −0.11 −0.02 0.001 0.001
 Second methylation 0.005 0.005 −0.00 0.01 −0.00 0.01 0.054 0.054
YAP polymorphism
 rs11225261 0.021 0.096 −0.24 0.28 −0.19 0.38 0.869 0.509
 rs1820453 −0.065 −0.08 −0.17 0.04 −0.23 0.06 0.236 0.249

Adjusted by smoking, type of drinking water, AsIII, AsV, iAs, DMAV, total As and first methylation.