Table 7.
OR | 95% CI | P-value | ||||
---|---|---|---|---|---|---|
Crude | Adjusted | Crude | Adjusted | Crude | Adjusted | |
Lifestyle factors | ||||||
Smoking | 2.05 | 1.87 | 1.09 3.85 | 0.94 3.74 | 0.025 | 0.073 |
Type of drinking water | 2.29 | 1.88 | 1.32 3.97 | 1.03 3.44 | 0.003 | 0.039 |
Urinary arsenic metabolites | ||||||
AsIII | 1.18 | 1.15 | 1.01 1.38 | 0.98 1.34 | 0.031 | 0.07 |
AsV | 1.18 | 1.16 | 1.04 1.33 | 1.02 1.31 | 0.01 | 0.02 |
iAs | 1.12 | 1.10 | 1.03 1.22 | 1.01 1.20 | 0.005 | 0.015 |
MMAV | 1.02 | 1.01 | 0.97 1.07 | 0.96 1.06 | 0.38 | 0.62 |
DMAV | 1.01 | 1.00 | 0.99 1.02 | 0.99 1.02 | 0.07 | 0.20 |
Total As | 1.00 | 1.00 | 0.99 1.02 | 0.99 1.01 | 0.06 | 0.17 |
As methylation profile | ||||||
First methylation | 0.47 | 0.48 | 0.31 0.70 | 0.32 0.74 | 0.000 | 0.001 |
Second methylation | 1.06 | 1.06 | 0.99 1.12 | 0.99 1.13 | 0.071 | 0.059 |
YAP polymorphisms | ||||||
rs11225261 | 1.30 | 1.50 | 0.40 4.23 | 0.44 5.04 | 0.65 | 0.50 |
rs1820453 | 0.70 | 0.68 | 0.38 1.29 | 0.36 1.30 | 0.25 | 0.25 |
Adjusted by smoking, type of drinking water, AsIII, AsV, iAs, DMAV, total As and first methylation.