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. Author manuscript; available in PMC: 2021 Mar 1.
Published in final edited form as: J Appl Toxicol. 2019 Oct 21;40(3):342–351. doi: 10.1002/jat.3907

Table 7.

Odds ratio (OR) for breast cancer and lifestyle factors, arsenic urinary levels and YAP polymorphism.

OR 95% CI P-value

Crude Adjusted Crude Adjusted Crude Adjusted
Lifestyle factors
 Smoking 2.05 1.87 1.09 3.85 0.94 3.74 0.025 0.073
 Type of drinking water 2.29 1.88 1.32 3.97 1.03 3.44 0.003 0.039
Urinary arsenic metabolites
 AsIII 1.18 1.15 1.01 1.38 0.98 1.34 0.031 0.07
 AsV 1.18 1.16 1.04 1.33 1.02 1.31 0.01 0.02
 iAs 1.12 1.10 1.03 1.22 1.01 1.20 0.005 0.015
 MMAV 1.02 1.01 0.97 1.07 0.96 1.06 0.38 0.62
 DMAV 1.01 1.00 0.99 1.02 0.99 1.02 0.07 0.20
 Total As 1.00 1.00 0.99 1.02 0.99 1.01 0.06 0.17
As methylation profile
 First methylation 0.47 0.48 0.31 0.70 0.32 0.74 0.000 0.001
 Second methylation 1.06 1.06 0.99 1.12 0.99 1.13 0.071 0.059
YAP polymorphisms
 rs11225261 1.30 1.50 0.40 4.23 0.44 5.04 0.65 0.50
 rs1820453 0.70 0.68 0.38 1.29 0.36 1.30 0.25 0.25

Adjusted by smoking, type of drinking water, AsIII, AsV, iAs, DMAV, total As and first methylation.