Table 4.
Multivariable Cox regressions: overall survival and recurrence-free survival of patients with rectal cancer
| HR | 95.0% CI for HR | p value | ||
|---|---|---|---|---|
| Lower | Upper | |||
| Overall survival | ||||
| Surgical approach | ||||
| Open | 1.000 | |||
| Laparoscopic | 0.819 | 0.747 | 0.899 | < 0.001 |
| Sex | ||||
| Male | 1.000 | |||
| Female | 0.803 | 0.745 | 0.864 | < 0.001 |
| Age at diagnosis | 1.063 | 1.059 | 1.067 | < 0.001 |
| Location rectum | ||||
| Lower rectum | 1.000 | |||
| Middle rectum | 0.993 | 0.895 | 1.101 | 0.890 |
| Upper rectum | 0.918 | 0.819 | 1.028 | 0.137 |
| Unspecified | 1.002 | 0.889 | 1.130 | 0.976 |
| Stage UICC | ||||
| I | 1.000 | |||
| II | 1.681 | 1.524 | 1.855 | < 0.001 |
| III | 2.276 | 2.077 | 2.495 | < 0.001 |
| Grading | ||||
| G1/2 | 1.000 | |||
| G3/4 | 1.192 | 1.085 | 1.310 | < 0.001 |
| Unspecified | 0.976 | 0.828 | 1.150 | 0.771 |
| Radio/chemotherapy neoadjuvant | ||||
| Yes | 1.000 | |||
| No | 1.163 | 1.071 | 1.264 | < 0.001 |
| Recurrence-free survival | ||||
| Surgical approach | ||||
| Open | 1.000 | |||
| Laparoscopic | 0.770 | 0.705 | 0.842 | < 0.001 |
| Sex | ||||
| Male | 1.000 | |||
| Female | 0.830 | 0.773 | 0.892 | < 0.001 |
| Age at diagnosis | 1.052 | 1.048 | 1.055 | < 0.001 |
| Location rectum | ||||
| Lower rectum | 1.000 | |||
| Middle rectum | 0.945 | 0.856 | 1.044 | 0.265 |
| Upper rectum | 0.896 | 0.804 | 0.999 | 0.047 |
| Unspecified | 0.930 | 0.829 | 1.042 | 0.212 |
| Stage UICC | ||||
| I | 1.000 | |||
| II | 1.647 | 1.499 | 1.811 | < 0.001 |
| III | 2.241 | 2.052 | 2.447 | < 0.001 |
| Grading | ||||
| G1/2 | 1.000 | |||
| G3/4 | 1.195 | 1.091 | 1.309 | < 0.001 |
| Unspecified | 0.976 | 0.836 | 1.141 | 0.763 |
| Radio-/chemotherapy neoadjuvant | ||||
| Yes | 1.000 | |||
| No | 1.166 | 1.077 | 1.263 | < 0.001 |
HR hazard ratio, CI confidence interval