Table 3.
Specific antibodies against HLA-A, -B, -C, -DP, -DQ, and -DR: logistic regression analysis in 273 older allogeneic stem cell transplantation candidates.
| Anti-HLA-A | Anti-HLA-B | Anti-HLA-C | Anti-HLA-DP | Anti-HLA-DQ | Anti-HLA-DR | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HR (95% CI) | P | HR (95% CI) | P | HR (95% CI) | P | HR (95% CI) | P | HR (95% CI) | P | HR (95% CI) | P | |
| Gender (female vs. male) | NS | NS | 2.729(1.404–5.303) | 0.003 | NS | 12.615(1.020–156.051) | 0.048 | NS | ||||
| Number of pregnancies | ||||||||||||
| 0 | 0.402(0.174–0.25) | 0.036 | 0.358(0.158–0.813) | 0.014 | NS | 0.254(0.082–0.790) | 0.018 | NS | ||||
| 1 | 0.243(0.118–0.501) | <0.001 | 0.169(0.082–0.350) | <0.001 | 2.026(0.164–25.056) | 0.582 | ||||||
| ≥2 | 1 | NS | 1 | NS | 1 | |||||||
| Number of total transfusions (>12 vs. ≤12) | NS | NS | NS | NS | NS | NS | ||||||
| Number of RBC transfusion (>7 vs. ≤7) | NS | NS | NS | NS | ||||||||
| Number of PLT transfusion (>7 vs. ≤7) | 2.444(1.227–4.868) | 0.011 | 2.279(1.131–4.594) | 0.021 | 2.678(1.266–5.663) | 0.010 | 8.259(3.357–20.318) | <0.001 | 6.810(2.889–16.053) | <0.001 | 5.398(2.426–12.011) | <0.001 |
Abbreviations: HLA, human leukocyte antigen; OR, odds ratio; CI, confidence interval; RBC, red blood cell; PLT, platelet.