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. 2020 Feb 11;10:2326. doi: 10.1038/s41598-020-59092-2

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Expression of Na_V and TRP channels in dorsal root ganglion neurons of Na_V1.7^−/−, Na_V1.8^−/−, Na_V1.9^−/− and wild type mice. (a,b) Relative mRNA expression compared to HPRT and respective agarose gels of amplified PCR products for Na_V, TRPA1 and TRPV1 channels. error bars: s.e.m, *P < 0.05 (c,d) Representative and quantitative immunohistochemistry of TRPA1 and TRPV1 expression, n = 3–5 (average from 4–7 slices per animal), error bars: s.e.m, scale bar: 100 µM.