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. 2020 Feb 11;10:2331. doi: 10.1038/s41598-020-59142-9

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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(A) Differentially expressed unique miRNAs in each cancer type. The bar graph represents the up and down-regulated unique miRNAs. The significant values are indicated in asterisk (*). (B) The heatmap of top 10 differentially expressed unique miRNAs from each cancer type. The heatmap represents the expression profile of unique miRNAs across seven-cancer type where each column is a cancer type. Each row is different miRNA specific to particular cancer. The colour key represents the expression pattern where red is for up-regulation, green for down-regulation and black for no expression.