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. 2020 Feb 11;10:2312. doi: 10.1038/s41598-020-59100-5

Table 2.

Correlations between the decline in the ESMCSAs and clinical parameters.

Variables r 95%CI P-value
Age, year −0.044 −0.244–0.156 0.637
Baseline body mass index, kg/m2 −0.175 −0.357–0.020 0.057
Baseline FVC, % predicted −0.285 −0.464–−0.089 0.002
Baseline FEV1/FVC, % 0.187 −0.009–0.369 0.042
Baseline DLCO, % predicted −0.172 −0.337–0.017 0.063
Baseline distance walked during 6MWT, m −0.171 −0.341–0.019 0.064
Baseline lowest SpO2 during 6MWT, % −0.290 −0.458–−0.101 0.002
Relative decline in FVC, % 0.202 0.022–0.358 0.028
Relative decline in DLCO, %* 0.083 −0.096–0.267 0.377
Relative decline in body mass index, % 0.394 0.217–0.552 <0.001

Abbreviations: ESMCSA;, cross-sectional areas of elector spine muscles; FVC, forced vital capacity; FEV1, forced expiratory volume in 1.0 second; DLCO, diffuse capacity of the lung for carbon monoxide; 6MWT, 6-minute walk test; SpO2, percutaneous oxygen saturation.

*We analysed using n = 114 because 5 cases were missing.