Table 1.
Characteristics of LEA participants at fasting status (N = 38).
| Trait | All | Sufficient EA (n = 26) | LEA (n = 12) | EUM (n = 11) | FHA (n = 27) |
|---|---|---|---|---|---|
| Age (years) | 26.5 [21.25;29] | 26 [21;30] | 27 [23.75;28] | 27 [23;31] | 26 [21;29] |
| HDL-C (mmol/l) | 1.8 [1.6;2.07] | 1.79 [1.43;2] | 1.99 [1.74;2.12] | 1.76 [1.29;2] | 1.86 [1.66;2.06] |
| LDL-C (mmol/l) | 2.3 [2.12;2.9] | 2.25 [1.95;2.9] | 2.3 [2.27;2.82] | 2.3 [2.25;2.5] | 2.3 [2;3.1] |
| TC (mmol/l) | 4.55 [4.1;5.1] | 4.35 [3.82;5.07] | 4.7 [4.45;5.12] | 4.6 [4;4.9] | 4.5 [4.1;5.3] |
| TG (mmol/l) | 0.67 [0.61;0.87] | 0.66 [0.58;0.79] | 0.68 [0.64;1] | 0.7 [0.66;0.91] | 0.66 [0.59;0.81] |
| Androstendion (nmol/l) | 4.82 [3.38;5.63] | 5.28 [3.26;5.63] | 4.09 [3.59;5.69] | 4.08 [3.06;4.76] | 5.26 [3.52;6.15] |
| DHAS (nmol/l) | 3238 [2455;4045] | 3300 [2675;5065] | 3229 [2134;3797] | 3020 [2176;3883] | 3360 [2955;4240] |
| Estrogen (ng/ml) | 0.12 [0.09;0.16] | 0.12 [0.09;0.15] | 0.14 [0.07;0.17] | 0.13 [0.12;0.18] | 0.11 [0.07;0.16] |
| Free testosterone (nmol/l) | 0.01 [0.01;0.02] | 0.02 [0.01;0.02] | 0.01 [0.01;0.02] | 0.01 [0.01;0.01] | 0.02 [0.01;0.02] |
| FSH (IU/l) | 6.5 [5.7;8.1] | 6.5 [5.92;8.1] | 6.8 [5.2;7.87] | 6.5 [5.85;7.75] | 6.5 [5.7;8.4] |
| LH (IU/l) | 4.15 [2.72;6.1] | 4.15 [2.35;6.7] | 4.5 [3.22;5.8] | 3.4 [2.9;5.15] | 4.9 [2.75;7.05] |
| Progesteron (ng/ml) | 1.23 [0.84;1.48] | 1.14 [0.74;1.47] | 1.28 [1.18;1.48] | 1.32 [0.96;1.55] | 1.18 [0.77;1.36] |
| Prolactin (IU/l) | 0.18 [0.13;0.24] | 0.15 [0.12;0.19] | 0.22 [0.18;0.27] | 0.22 [0.18;0.26] | 0.15 [0.11;0.21] |
| SHBG (nmol/l) | 69 [60;88] | 69 [59;87] | 70 [63;89] | 69 [56;83] | 70 [61;97] |
| Total testosterone (nmol/l) | 1.14 [0.82;1.34] | 1.17 [0.82;1.34] | 1.06 [0.82;1.3] | 0.81 [0.51;1.19] | 1.17 [0.91;1.46] |
| ACTH (µg/l) | 22 [17;36] | 21 [16;36] | 24 [22;30] | 15 [13;24] | 23 [19;37] |
| BDNF (µg/l) | 117 [78;164] | 124 [90;160] | 111 [64;168] | 138 [112;163] | 107 [72;163] |
| Cortisol (mmol/l) | 470 [393;550] | 478 [398;554] | 458 [380;537] | 424 [279;461] | 510 [423;555] |
| GH (ng/ml) | 4.2 [2.46;6.96] | 4.36 [2.46;8.14] | 3.76 [2.73;4.79] | 2.9 [2.01;5.77] | 4.73 [2.74;7.16] |
| Insulin (mIE/l) | 3.25 [2.41;5.4] | 3.7 [2.62;6.62] | 2.7 [2.25;3.6] | 2.7 [2.2;4.6] | 3.3 [2.58;6.15] |
| Leptin (µg/ml) | 2942 [1621;3875] | 2151 [397;3549] | 3170 [2915;4190] | 3119 [1772;4988] | 2608 [794;3524] |
| TSH (mIU/l) | 2.16 [1.69;2.86] | 2.23 [1.53;2.86] | 2.1 [1.96;2.66] | 2.05 [1.4;2.54] | 2.18 [1.77;2.92] |
| BMD (kg/cm2) | 1.11 [1.05;1.14] | 1.1 [1.05;1.14] | 1.12 [1.05;1.13] | 1.13 [1.09;1.13] | 1.09 [1.05;1.14] |
| BMI (kg/m2) | 20.35 [19.21;21.37] | 20.19 [18.83;21.19] | 20.8 [20;21.52] | 20.8 [20.29;22.03] | 20.2 [18.85;21.04] |
| Fat mass (%) | 20.25 [18.07;22.3] | 19.7 [17.47;21.37] | 21.35 [19.87;23.7] | 20.8 [19.9;24.45] | 19.8 [17.25;21.75] |
Abbreviations: ACTH - adrenocorticotropic hormone; BDNF - brain-derived neurotrophic factor; BMD - bone mineral density; BMI - body mass index; DHAS - dehydroepiandrosterone; EA - energy availability; EUM - eumenorrhea; FHA - functional hypothalamic amenorrhea; FSH - follicle stimulating hormone; GH - growth hormone; HDL-C - high-density lipoprotein cholesterol; LDL-C - low-density lipoprotein cholesterol; LEA - low energy availability; LH - luteinizing hormone; SHBG - sex hormone binding globulin; TC - total cholesterol; TG - triglycerides; TSH - thyroid stimulating hormone.
The values shown are median values and interquartile ranges.