Table 1.
Demographic characteristics and neuropsychological test results.
| Characteristic | NC (n = 38) | MCI (n = 40) | AD (n = 19) | Test statistic | P-value |
|---|---|---|---|---|---|
| Age (y) | 75.1 ± 1.6 | 75.3 ± 1.1 | 74.6 ± 2.3 | F = 0.04 | 0.96 |
| Sex (male/female) | 19/19 | 20/20 | 11/8 | x2 = 0.381 | 0.826 |
| Education level (y) | 17.0 ± 0.4 | 15.6 ± 0.5 | 15.4 ± 0.5 | F = 3.55 | 0.033ab |
| CDR | 0.03 ± 0.02 | 0.49 ± 0.07 | 1.00 ± 0.11 | F = 54.59 | <0.001abc |
| FAQ | 0.08 ± 0.06 | 3.10 ± 0.77 | 15.06 ± 2.04 | F = 39.33 | <0.001abc |
| MMSE | 29.24 ± 0.17 | 27.90 ± 0.29 | 21.53 ± 1.08 | F = 73.98 | <0.001abc |
| MoCA | 25.00 ± 0.39 | 20.05 ± 0.91 | 13.87 ± 1.35 | F = 48.68 | <0.001abc |
| GDS | 0.50 ± 0.12 | 1.83 ± 0.25 | 1.84 ± 0.32 | F = 12.84 | <0.001ab |
AValues are given as the mean ± SD.
BNC, normal control; MCI, amnestic mild cognitive impairment; AD, Alzheimer's disease; CDR, Clinical Dementia Rating Scale; FAQ, Functional Activities Questionnaire; MMSE, Mini-Mental State Examination; MoCA, Montreal Cognitive Assessment; GDS, Geriatric Depression Scale.
a
NC group and MCI patients showed significant differences (P < 0.05).
b
NC group and AD patients showed significant differences (P < 0.05).
c
MCI patients and AD patients showed significant differences (P < 0.05).