Table 3.

Partial Pearson's correlations between connection density and coupling metric with clinical performance.

COV: Sex & Age		CDR	FAQ	MMSE	MoCA	GDS
Rich-club density	r	0.193	0.339	0.461	0.152	0.192
	P	0.099	0.011*	0.001**	0.157	0.101
Feeder density	r	0.428	0.446	0.459	0.252	0.193
	P	0.001**	0.001**	0.001**	0.046*	0.100
Local density	r	0.304	0.284	0.254	0.123	0.179
	P	0.020*	0.028*	0.044*	0.208	0.117
SC-FC coupling	r	0.531	0.559	0.409	0.347	0.062
	P	<0.001***	<0.001***	0.002**	0.009**	0.342
Rich-club coupling	r	0.054	0.126	0.155	0.075	0.042
	P	0.361	0.201	0.153	0.310	0.391
Feeder coupling	r	0.392	0.389	0.283	0.291	0.079
	P	0.004**	0.004**	0.028*	0.025*	0.302
Local coupling	r	0.339	0.406	0.345	0.266	0.031
	P	0.011*	0.003**	0.009**	0.037*	0.420

Partial Pearson's correlations controlled for age and sex were used to assess how connection density and coupling related to clinical performance. The star-labeled numbers represent significant correlations (^*P < 0.05, ^**P < 0.01,^***P < 0.001). Bold Font indicated significant correlation (P < 0.05).