Table 2.
Event | Treatment‐related grade 1‐2 | Grade 3‐4 (any attribution) | ||
---|---|---|---|---|
No of patients | % | No of patients | % | |
Cardio‐renal | ||||
Hyponatremia | 1 | 6 | ||
Constitutional | ||||
Fatigue or lethargy | 5 | 29 | ||
Flu‐like symptoms | 2 | 12 | ||
Hot flashes | 1 | 6 | ||
Myalgias | 1 | 6 | ||
Dermatologic | ||||
Injection site reactions | 16 | 94 | ||
Pruritus | 2 | 12 | ||
Rash | 2 | 12 | ||
Endocrine | ||||
Hypothyroidism | 4 | 24 | ||
Gastrointestinal | ||||
Anorexia | 1 | 6 | ||
AST elevation | 1 | 6 | ||
Hematologic | ||||
Anemia (hemolytic) | 1 | 6 | ||
Anemia (non‐hemolytic) | 1 | 6 | ||
Other | ||||
Corneal transplant rejection | 1 | 6 | ||
CPK increased | 1 | 6 | ||
Hip fracture | 1 | 6 | ||
Pulmonary | ||||
Shortness of breath | 1 | 6 |
Abbreviation: AST, aspartate aminotransferase; CPK, creatine phosphokinase.