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Flow chart of inclusion and exclusion in the study. The cohort 1 was for the analysis of distant metastasis mode and cox regression. The cohort 2 was for the survival analysis of chemotherapy efficacy and was built up by integrating the five subgroups. AVC, Carcinoma of Vater ampulla; BTC, biliary tract cancer DCC, Distal cholangiocarcinoma; GBC, Gallbladder cancer; ICC, Intrahepatic cholangiocarcinoma; PHCC, Perihilar cholangiocarcinoma; PS, Propensity score
