Table 2.
Characteristics of patients in hepatocellular carcinoma (HCC) and intrahepatic cholangiocarcinoma (ICC)
| Variables | HCC (n = 375) | ICC (n = 47) | P value |
|---|---|---|---|
| Demographics and history | |||
| Age (years) | 52.29 ± 11.44 | 56.04 ± 10.35 | .033 |
| Sex | |||
| Man | 331 | 27 | <.001 |
| Woman | 44 | 20 | |
| BMI | 23.03 ± 3.22 | 23.04 ± 3.08 | .985 |
| Diabetes | |||
| No | 347 | 45 | .558 |
| Yes | 28 | 2 | |
| Hypertension | |||
| No | 304 | 39 | .845 |
| Yes | 71 | 8 | |
| Etiology | |||
| Hepatitis | 327 | 14 | <.001 |
| Others | 48 | 33 | |
| Preoperative blood tests | |||
| ICG‐R15 (%) | 6.16 ± 6.52 | 4.69 ± 3.49 | .213 |
| AFP (ng/mL) | 320.05 ± 439.77 | 36.46 ± 178.37 | <.001 |
| CEA (ng/mL) | 2.79 ± 4.19 | 8.34 ± 23.20 | .108 |
| CA199 (ng/mL) | 26.79 ± 28.16 | 242.98 ± 324.79 | <.001 |
| ALB (g/L) | 40.99 ± 4.53 | 41.71 ± 4.58 | .310 |
| TBIL (μmol/L) | 14.62 ± 10.64 | 18.25 ± 28.36 | .389 |
| DBIL (μmol/L) | 6.78 ± 7.26 | 8.03 ± 13.55 | .538 |
| ALT (U/L) | 44.01 ± 40.55 | 44.02 ± 41.19 | .999 |
| AST (U/L) | 50.68 ± 46.70 | 41.31 ± 28.67 | .180 |
| PT (s) | 13.99 ± 6.23 | 13.01 ± 0.84 | .284 |
| INR | 1.07 ± 0.10 | 1.02 ± 0.07 | <.001 |
| Neutrophil (109/L) | 3.47 ± 2.32 | 5.01 ± 2.29 | <.001 |
| Lymphocyte (109/L) | 1.54 ± 1.01 | 1.46 ± 0.62 | .588 |
| Monocyte (109/L) | 0.82 ± 1.74 | 0.75 ± 1.01 | .791 |
| Platelet (109/L) | 156.90 ± 74.21 | 218.55 ± 68.55 | <.001 |
| HB (g/L) | 143.37 ± 70.76 | 132.98 ± 17.00 | .371 |
| NLR | 2.59 ± 1.70 | 4.13 ± 4.25 | .018 |
| PLR | 116.07 ± 70.77 | 169.00 ± 78.17 | <.001 |
| LMR | 3.41 ± 1.82 | 2.78 ± 1.47 | .023 |
| APRI | 1.26 ± 5.66 | 0.51 ± 0.35 | .356 |
| ANRI | 17.68 ± 18.41 | 9.24 ± 6.53 | <.001 |
| Preoperative imaging | |||
| Tumor number | |||
| Solitary | 320 | 42 | .657 |
| Multiple | 55 | 5 | |
| Tumor size (cm) | 6.35 ± 4.79 | 7.00 ± 2.78 | .364 |
| Ascites | |||
| No | 346 | 47 | .620 |
| Yes | 11 | 0 | |
Categorical variables are expressed as frequency. Continuous variables are expressed as mean ± standard deviation.
ICG‐R15, indocyanine green retention rate at 15 min.
Abbreviations: AFP, α‐fetoprotein level; ALB, albumin; ALT, alanine transaminase; ANRI, AST‐to‐neutrophil ratio index; APRI, AST‐to‐platelet ratio index; AST, aspartate transaminase; CA199, cancer antigen 199; CEA, carcinoembryonic antigen; DBIL, direct bilirubin; INR, international normalized ratio; LMR, lymphocyte‐to‐monocyte ratio; NLR, neutrophil‐to‐lymphocyte ratio; PLR, platelet‐to‐lymphocyte ratio; PT, prothrombin time; PTA, prothrombin activity; TBIL, total bilirubin.
Bold indicates statistically significant values (P < .05).