Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2020 Feb 5;11:120. doi: 10.3389/fimmu.2020.00120

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2020 Herrera-Rios, Mughal, Teuber-Hanselmann, Pierscianek, Sucker, Jansen, Schimming, Klode, Reifenberger, Felsberg, Keyvani, Brors, Sure, Reifenberger, Schadendorf and Helfrich.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

Comparative analyses of intratumoral and peritumoral IDO-expression in human melanoma metastases of intracranial and extracranial origin. The total number of IDO-positive cells localized in the tumor (intratumoral) or around (peritumoral) in (A) ICM and (B) ECM was quantified in accordance to histopathological labeling of the tumor area by using the quantitative digital pathology tissue analysis system Definiens Tissue Studio (n ICM = 48/47 patients, n ECM = 18/16 patient, n matched-pairs = 16; **p < 0.05). To ensure statistical balance between both parameters we excluded all patient samples from the analyses in the case of missing stroma in the individual tissue specimen.