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The intracellular c-di-GMP concentration in wild-type and mutant strains of Y. enterocolitica. Bacteria were cultured in LNNS medium supplemented with 0.6 g/L L-arabinose at 26°C. Intracellular c-di-GMP levels were analyzed in bacteria grown to the exponential phase. The data are presented as the mean ± SD of at least three independent experiments. An asterisk indicates a significant difference with ***P < 0.001, **P < 0.01, *P < 0.05.
