Section and topic	No.	Quality criteria	Yes	No
Title/Keywords/Introduction	1	Were the study hypothesis/aim/objective clearly described
Method	2	Were the animal model for the study well-described
	3	Were the method well-described
	4	Were the data collected time point clearly defined
	5	Were the main outcome measures clearly defined
	6	Were the experiment group well compared with the control group
Discussion	7	Were the results well-described
	8	Were the articles discussed the limitation

Kathleen Wells, Julia H. Littell. Study Quality Assessment in Systematic Reviews of Research on Intervention Effects. Research on Social Work Practice. 2009; 19: 52–62.