Table 1.
Vector | Recombinant Molecule Type | No. of Genes | Brief Method |
---|---|---|---|
cB72.3 | IgG4 | 2 | Vector used to generate cells stably expressing cB72.3 molecule using hosts previously engineered to overexpress LMM molecules. Vector used to transiently produce cB72.3 molecule. |
Fc-Fusion Protein | Fc fusion protein (FcFP) | 1 | Vector used to generate cells stably expressing an Fc fusion protein using hosts previously engineered to overexpress LMM molecules. Vector used to transiently produce an Fc fusion protein. |
IL2-F-Control | Interleukin 2 fused bispecific antibody | 3 plus LMM gene | Vectors bearing both IL2-F genes and LMM genes used to transiently co-transfect. |
IL2-F-SCD1 | |||
IL2-F-SREBF1 | |||
IL-2-F | Interleukin 2 fused bispecific antibody | 3 | Vector used to generate cells stably expressing IL2-F molecule using hosts previously engineered to overexpress LMM molecules. |
DTE-IgG1 | IgG1 | 2 | Vector used to generate cells stably expressing DTE-IgG1 molecule using hosts previously engineered to overexpress LMM molecules. |