Figure 5.

miR-570-3p Promotes the Migration and Invasion of BCa Cells

(A and B) The migration and invasion abilities of T24 and UM-UC-3 cells transfected with miR-570-3p mimic were measured by Transwell (A) and wound-healing (B) assays. (C and D) The migration and invasion abilities of T24 and UM-UC-3 cells transfected with miR-570-3p inhibitor were evaluated by Transwell (C) and wound-healing (D) assays, and the times for Transwell assays were as follows: 10 h (T24) and 25 h (UM-UC-3) for migration; 15 h (T24) and 34h (UM-UC-3) for invasion. (E) The abundance of miR-570-3p in BCa tissues and matched normal bladder tissues detected by quantitative real-time PCR (n = 50). (F) The correlation between circFUT8 and miR-570-3p in BCa tissues (n = 49, and one extreme value was excluded). Scale bars, 100 μm. Data are presented as the mean ± SEM of three experiments. *p < 0.05; **p < 0.01, Student’s t test.