Figure 2.

The expression levels of candidate circRNAs. Results were obtained by performing RT-qPCR in triplicate. RNA expression levels were normalized to expression of the reference gene GAPDH. A. The expression of circRNAs in A549, H1299, and H460 lung cancer cells were compared to the expression in BEAS-2B normal lung cells. Results represent the mean ± SD. B. The average expression of circRNAs in 61 pairs of NSCLC tissues (case) and adjacent lung tissues (control). C. The expression of ABCA3 mRNA in lung cancer cells (left panel) and tissues (right panel). ****P < 0.001. Abbreviations: ABCA3, ATP binding cassette subfamily A member 3; GAPDH, glyceraldehyde-3-phosphate dehydrogenase; NSCLC, non-small cell lung cancer.