Figure 3.
F1/F3 gel inhibits TC-1 tumor growth in vivo. Groups of five C57/BL6 mice were subcutaneously transplanted with 5×105 TC-1 tumor cells. When the tumors reached 3 mm in diameter, the mice were injected intratumorally with 100 µl PBS containing 30 µg of F1 and F3 peptide or F1/F3 gel for 7 days consecutively. Control groups received PBS or gel only. Then, 3 days after final injection, tumors were isolated from individual mice and analyzed for (A) volume and (B) weight. Each bar represents the means of measurements of tumors from the five mice, and the error bars represent the standard deviations. *P<0.05; ****P<0.0001; ns, not significant.