Darwish 2016.
Methods | Parallel randomised controlled trial conducted in Womens Health University Hospital, Eygpt Timing: June 2013 to November 2014 |
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Participants | 88 women randomised. 80 women analysed. Mean age of women in monopolar group was 25 ± 4.7 years and for the bipolar group was 24.8 ± 4.4 years Inclusion criteria: Clomiphene‐resistant PCOS (Rotterdam 2003) Exclusion criteria: Male‐factor infertility, tubal or peritoneal factor infertility and endometriosis. One or both tubes blocked. Pelvic adhesions |
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Interventions | Monopolar LOD: monopolar needle. 4 seconds with 40 W, 4 punctures to each ovary. Energy for each ovary 640 J (n = 45), versus Bipolar LOD: bipolar needle. 4 seconds with 40 W, 4 punctures to each ovary. Energy for each ovary 640 J (n = 43) Follow‐up for 6 months |
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Outcomes | Regularity of menstrual cycle, ovulation rate, pregnancy rate | |
Notes | No conflict of interest No funding Clinical trial registration number: not stated |
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Risk of bias | ||
Bias | Authors' judgement | Support for judgement |
Random sequence generation (selection bias) | Low risk | Quote: "randomly assigned" "computerized random table" |
Allocation concealment (selection bias) | Unclear risk | No details provided |
Blinding of participants and personnel (performance bias) All outcomes | Unclear risk | No details provided |
Blinding of outcome assessment (detection bias) All outcomes | Unclear risk | No details provided |
Incomplete outcome data (attrition bias) All outcomes | Low risk | 45 women allocated to monopolar group; 5 cases lost to follow‐up due to difficulty in travelling and follow‐up by own doctor 43 women allocated to bipolar group; 3 cases lost to follow‐up due to difficulty in travelling and follow‐up by own doctor |
Selective reporting (reporting bias) | Unclear risk | We could not retrieve the original protocol. The outcomes mentioned in the Methods section are presented in the Results section |
Other bias | Low risk | No evidence of other risk of bias |