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. 2020 Feb 11;2020(2):CD001122. doi: 10.1002/14651858.CD001122.pub5

Darwish 2016.

Methods Parallel randomised controlled trial conducted in Womens Health University Hospital, Eygpt
Timing: June 2013 to November 2014
Participants 88 women randomised. 80 women analysed. Mean age of women in monopolar group was 25 ± 4.7 years and for the bipolar group was 24.8 ± 4.4 years
Inclusion criteria: Clomiphene‐resistant PCOS (Rotterdam 2003)
Exclusion criteria: Male‐factor infertility, tubal or peritoneal factor infertility and endometriosis. One or both tubes blocked. Pelvic adhesions
Interventions Monopolar LOD: monopolar needle. 4 seconds with 40 W, 4 punctures to each ovary. Energy for each ovary 640 J (n = 45), versus
Bipolar LOD: bipolar needle. 4 seconds with 40 W, 4 punctures to each ovary. Energy for each ovary 640 J (n = 43)
Follow‐up for 6 months
Outcomes Regularity of menstrual cycle, ovulation rate, pregnancy rate
Notes No conflict of interest
No funding
Clinical trial registration number: not stated
Risk of bias
Bias Authors' judgement Support for judgement
Random sequence generation (selection bias) Low risk Quote: "randomly assigned" "computerized random table"
Allocation concealment (selection bias) Unclear risk No details provided
Blinding of participants and personnel (performance bias) 
 All outcomes Unclear risk No details provided
Blinding of outcome assessment (detection bias) 
 All outcomes Unclear risk No details provided
Incomplete outcome data (attrition bias) 
 All outcomes Low risk 45 women allocated to monopolar group; 5 cases lost to follow‐up due to difficulty in travelling and follow‐up by own doctor
43 women allocated to bipolar group; 3 cases lost to follow‐up due to difficulty in travelling and follow‐up by own doctor
Selective reporting (reporting bias) Unclear risk We could not retrieve the original protocol. The outcomes mentioned in the Methods section are presented in the Results section
Other bias Low risk No evidence of other risk of bias