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. 2020 Feb 11;2020(2):CD001122. doi: 10.1002/14651858.CD001122.pub5

El‐Sayed 2017.

Methods Parallel arm "randomized clinical study" conducted in Zagazig University Hospital, Egypt
Timing: November 2015 to January 2017
Participants 100 women randomised (50 per group), 95 women analysed (48 in group 1 and 47 in group 2). Mean age: Group 1: 27.5 ± 4.25; Group 2: 28.03 ± 4.32
Inclusion criteria: Infertile women with clomiphene citrate‐resistant PCOS (150 mg/day for 5 days), aged between 25 and 35 years, infertility duration of ≤ 3 years, BMI < 30 kg/m2 luteinising hormone ≥ 10 IU/ml or LH/FSH ratio ≥ 2, Free androgen index ≥ 4, normal semen analysis in the husband, normal oral glucose tolerance test
Exclusion criteria: Hyper‐androgenic disorders such as late onset congenital adrenal hyperplasia, hyperprolactinaemia, thyroid diseases, Cushing's syndrome, androgen‐secreting tumours
Interventions Unilateral laparoscopic ovarian surgery on the right side, using thermal dose adjusted according to ovarian volume (n = 50), versus
Bilateral laparoscopic ovarian surgery using thermal dose adjusted to ovarian volume on both sides (n = 50)
Follow‐up for 6 months
Outcomes Menstrual cycle resumption, ovulation rate, cumulative pregnancy rate
Notes Further information confirming methods requested from authors 2 August 2017
No conflict of interest
Clinical trial registration number: not stated
Risk of bias
Bias Authors' judgement Support for judgement
Random sequence generation (selection bias) Low risk Randomisation was done using a computer
Allocation concealment (selection bias) Unclear risk No details in the paper
Blinding of participants and personnel (performance bias) 
 All outcomes Unclear risk No details in the paper but unlikely to have occurred
Blinding of outcome assessment (detection bias) 
 All outcomes Unclear risk No details in the paper
Incomplete outcome data (attrition bias) 
 All outcomes Low risk Unilateral LOD group: 2 participants excluded; 1 had a tubal disease which was identified during laparoscopy and 1 missed the follow‐up
Bilateral LOD group: 3 participants excluded; 1 was excluded due to endometriosis which was diagnosed during laparoscopy, and 2 participants missed follow‐up
Selective reporting (reporting bias) Unclear risk We could not retrieve the original protocol. The outcomes mentioned in the Methods section are presented in the Results section
Other bias Low risk No evidence of other risk of bias